D. Hristu-Varsakelis

Professor, Department of Applied Informatics


University of Macedonia




" Dimitrios Hristu-Varsakelis is a Professor in the Department of Applied Informatics. He received his Ph.D. in Engineering Sciences and M.S. in Applied Mathematics from the Division of Engineering and Applied Sciences at Harvard University. He has held faculty positions in the Department of Mechanical Engineering and the Institute for Systems Research at the University of Maryland, College Park.

Some of his research has dealt with problems of stability and optimal control in networked control systems, machine learning-based optimization and prediction, bio-inspired cooperative optimal control, and provably secure cryptographic protocols. His current interests are in the areas of optimization, machine learning, decision and control, and dynamics of socio-economic systems. He is also involved in the mentoring and advising of innovators and startup companies in related areas.










Research

Machine Learning in Medicine

We are developing advanced machine learning-based approaches to clinically relevant problems, such as estimating the left ventricular ejection fraction using echocardiogram video, detecting paroxysmal atrial fibrillation from sinus-rhythm electrocardiogram, and predicting which atrial fibrillation patients are good candidates for ablation.

Machine learning based stock prediction, trading and portfolio construction

We explore the use of novel deep LSTM and other architectures for predicting asset prices, in conjunction with trading strategies that generate profits based on the networks' predictions. Our work takes advantage of the fact that the effectiveness of any prediction model is inherently coupled to the trading strategy it is used with (and vice versa) which makes the design of models and strategies which are jointly optimal especially challenging. Our architectures far outperform market benchmarks when trading on major US stock indices.

Bio-inspired optimization in dynamic environments

Using the process via which ants optimize their trails when traversing previously unknown terrain, we are developing algorithms for solving challenging trajectory optimization problems in settings where the environment is time-varying and contains moving obstacles or other dynamic "no-go" regions.

Tax Optimization via Deep Learning

We are exploring stochastic and Markov-based models of the process via which economic agents (e.g. small businesses or corporations) make tax-related decisions, including whether or not to keep from disclosing income, where conditions allow. Using techniques from optimal control and machine learning, we are developing computational tools for evaluating tax policies and for examining the effects of proposed changes in the tax code, before they are adopted in vivo.



Publications

  • D. Hristu-Varsakelis, "Optimal Control with Limited Communication", Ph.D. Thesis, Division of Engineering and Applied Sciences, Harvard University, June 1999.
  • D. Hristu, "Dexterous Manipulation with Multi-fingered Hands", M.Sci. Thesis, Department of Electrical Computer and Systems Engineering, Rensselaer Polytechnic Institute, May 1994.
  • D. Hristu-Varsakelis, P. S. Krishnaprasad, F. Zhang, S.Andersson, L. D'Anna, P. Sodre,"The MDle Engine: A Software Tool for Hybrid Motion Control", Institute for Systems Research, Technical Report TR2000-54.
  • K. Hitchcock, D. Hristu-Varsakelis and A. Johnson, "Quadricuspid flow control valve", University of Maryland Invention Disclosure #PS-2004-087.


Teaching

Mathematical Analysis

Introduction to Mathematical Analysis. Sequences and Series. Convergence. Taylor series. Derivatives. Differentiation of multi-variable functions. Multivariable optimization. Optimization with an equality constraint. Optimization with interval bounds. Introduction to differential and difference equations. Solving linear ODEs and difference equations. Second-order systems.

Course Website
DAI-106

Fall semester

AIDA-101

Fall Semester (-2024)

Probabilistic Modeling and Reasoning

The course is part of the department's newest MS program in Artificial Intelligence and Data Analytics (AIDA), and covers the background necessary to successfully navigate the program; Probability, discrete belief networks, inference; Parameter estimation, hidden variable models, dynamic hidden variable models; Entropy, mutual information, Kullback-Leibler divergence; Approximate inference methods, E-M algorithm, sampling methods.

Course website

Operations Research

Linear vector spaces, multi-variable optimization, linear programming, the Simplex algorithm, duality, sensitivity analysis. Nonlinear programming, Lagrange multipliers, KKT problems. Numerical methods. Integer programming, Branch-and-Bound method.

Course website
DAI-120

Spring semester

DAI-185

Spring Semester

Optimization and Decision Making

Introduction to Decision Making in structured and semi-structured settings. Decision Trees. Utility Theory. Introduction to discrete-time dynamical systems. Dynamic Programming. Markov-based models, Value iteration, Policy iteration. Optimal stopping problems. Real-world decision making and factors that affect human decisions.

Course website

Quantitative Methods (Hellenic Open University)

Functions, limits, continuity, derivatives. Optimization of single-variable functions. Probability and random variables. Descriptive statistics. Discrete and continuous distributions. Probabilistic inference.

Course description @HOU
DHD-22

Fall/Spring semester

Contact

Student contact hours

here

Email

dcv @ uom.edu.gr

Phone

+30 2310 891 721

Location

Thessaloniki, Greece

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